Samuel Ehiabhi OKHALE, PhD.

Professor (Associate), Chemistry

Garki, Abuja, NG.

About

Distinguished Associate Professor of Chemistry with over two decades of expertise in pharmaceutical sciences, natural products chemistry, and advanced analytical techniques, leading comprehensive research initiatives and managing ISO/IEC 17025 accredited laboratories. Drives innovation in drug discovery and quality assurance while supervising M.Sc and PhD students and contributing significantly to national pharmaceutical policy and training.

Work

National Institute for Pharmaceutical Research and Development (NIPRD)

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Professor (Associate)

Abuja, F.C.T., Nigeria

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Summary

Leads comprehensive research in pharmaceutical sciences, natural products chemistry, and advanced analytical techniques, while managing ISO/IEC 17025 accredited laboratories and supervising M.Sc and PhD students.

Highlights

Directed extensive research in natural products chemistry, organic synthesis, and advanced spectroscopy, contributing to the isolation and characterization of bioactive compounds.

Managed chemical and pharmaceutical reference standards, ensuring compliance and quality for critical research and development processes.

Supervised numerous M.Sc and PhD students in Natural Products/Synthetic Organic Chemistry, fostering the next generation of scientific expertise.

Served as Coordinator and Quality Assurance Manager for NIPRD ISO/IEC 17025:2017 Accredited Testing Laboratories, ensuring adherence to international quality standards.

Applied expertise as an ISO 9001 Quality Management System (QMS) expert, optimizing laboratory processes and operational efficiency.

Nigeria Breweries Limited Ibadan

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Laboratory Equipment, Scientific and Technical Training Consultant

Ibadan, Oyo, Nigeria

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Summary

Provided expert consultation on laboratory equipment and delivered scientific and technical training to enhance operational capabilities.

Highlights

Consulted on laboratory equipment, optimizing procurement and utilization for enhanced research and production efficiency.

Delivered scientific and technical training, improving staff competency in laboratory operations and data analysis.

Medac Pharmaceutical Productions Limited

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Quality Assurance Manager

Oyo State, Oyo, Nigeria

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Summary

Performed analytical chemistry functions and managed quality control and assurance functions, overseeing drug manufacturing process control.

Highlights

Managed and executed analytical chemistry functions, ensuring precise and reliable results for pharmaceutical production.

Directed quality control and quality assurance processes, maintaining high standards for drug manufacturing.

Oversaw drug manufacturing process control, implementing protocols to enhance product safety and efficacy.

Abiodun Atiba Memorial Institute

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Chemistry Lecturer

Oyo State, Oyo, Nigeria

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Summary

Taught chemistry courses and organized practical sessions, fostering student understanding and skill development in chemical principles.

Highlights

Instructed students in fundamental and advanced chemistry principles, achieving high rates of student comprehension.

Designed and facilitated chemistry practicals, providing hands-on experience and reinforcing theoretical knowledge.

Developed curriculum materials and assessment strategies to support effective learning outcomes for chemistry students.

Education

Ahmadu Bello University, Zaria

Zaria, Kaduna, Nigeria
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Ph.D. Chemistry

Courses

Hydrochloric Acid-Catalysed Rearrangement Reaction of 7-Deacetoxy-7a-hydroxygedunin and Antimicrobial Activity Studies of the Rearrangement Products.

University of Ibadan, Ibadan, Nigeria

Ibadan, Oyo State, Nigeria
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M.Sc. Organic Chemistry

Courses

Essential Oil Analyses and Antimicrobial Activities of Anacardium occidentalis and Voacanga africana.

University of Ibadan, Ibadan, Oyo State

Ibadan, Oyo State, Nigeria
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B.Sc. (Hons.) Chemistry Grade: 2nd Class Upper Division

Courses

Production of Natural Rubber Adhesive from Rubber Latex.

Government Secondary School, Bosso, Minna

Bosso, Minna, Niger state, Nigeria
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SSSCE Cert. Senior Secondary School Certificate

Awards

Best Staff Award for Research Fellow MPR&TM Department

NIPRD

Honored as the top-performing research fellow in the Medicinal Plant Research & Traditional Medicine Department.

ISO 9001 Quality Management System Certified Auditor of NIPRD (With Highest Score of 83% in the Auditors Examination)

NIPRD

Recognized for achieving the highest score (83%) in the auditors examination for ISO 9001 Quality Management System certification.

Excellence in Service Award

NIPRD

Received for long and meritorious service to NIPRD, demonstrating sustained commitment and impact.

Special commendation for participation in NIPRD Quality Management System certification

NIPRD

Recognized for significant contributions to NIPRD's Quality Management System certification process.

Commendation for excellent performance as a member of the Programme and Exhibition Committee

NIPRD

Commended for instrumental role in the commissioning of the NIPRD New Administrative and Laboratory Complex.

Co-Winner World Bank Research Grant No. FME/STEPB /79/3/22 (STEP-B NIPRD Antidiabetic Phytomedicine Development Project)

World Bank / NIPRD

Recognized for outstanding contribution to the Antidiabetic Phytomedicine Development Project.

The Most Outstanding PhD Student Poster Award

NIPRD/NIH Research Continuum in Natural Products Drug Discovery Symposium

Awarded for an exceptional poster presentation at the Natural Products Drug Discovery Symposium.

Publications

In vitro activity of Extract and Fractions of Albizia chevalieri Harms (Mimosaceae) Stem Bark against Trypanosoma brucei brucei. Trop J Phytochem Pharm Sci, February2025; 4(2): 63 -67

Trop J Phytochem Pharm Sci

Investigated the in vitro activity of Albizia chevalieri stem bark extracts and fractions against Trypanosoma brucei brucei.

GC-MS Analysis, Anxiolytic and Anti-Epileptogenic Effects of Combretum nigricans Leaf Extract in Laboratory Animals. Advances in Pharmacology and Pharmacy 13(3): 368-376, 2025.

Advances in Pharmacology and Pharmacy

Analyzed Combretum nigricans leaf extract using GC-MS and evaluated its anxiolytic and anti-epileptogenic effects in laboratory animals.

Evaluation of the Antioxidant, Antinociceptive and Anti-inflammatory Activities of Combretum nigricans Ethanol Leaf Extract. Tropical Journal of Natural Product Research, June 2024; 8(6): 7554-7560

Tropical Journal of Natural Product Research

Evaluated the antioxidant, antinociceptive, and anti-inflammatory properties of Combretum nigricans ethanol leaf extract.

Synergistic Antimicrobial Activities and Phytochemical Analysis of Leaf Extracts from Sarcocephalus latifolius, Morinda lucida and Anogeissus leiocarpus. Asian Science Bulletin, 2(4): 425-434, 2024

Asian Science Bulletin

Conducted phytochemical analysis and evaluated synergistic antimicrobial activities of leaf extracts from Sarcocephalus latifolius, Morinda lucida, and Anogeissus leiocarpus.

Chemical Composition Analysis of Eucalyptus citriodora Essential Oil Using GC-MS and NMR Spectroscopy. Trends Agric. Sci., 2024, 3 (2): 83-90

Trends Agric. Sci.

Analyzed the chemical composition of Eucalyptus citriodora essential oil using GC-MS and NMR spectroscopy.

Languages

English

Certificates

USP Development of Reference Standards and how to mitigate risks webinar

USP

Inaugural Africa Chapter Meeting of the United States Pharmacopeia (USP)

United States Pharmacopeia (USP)

Certification in Artificial Intelligence and Machine Learning as a 3MTT Academy NextGen Cohort Fellow (in view)

3MTT Academy

Alison online certifications in Prompt Engineering for Artificial Intelligence Applications

Alison

Alison online certifications in Artificial Intelligence for Task Management & Productivity

Alison

Alison online certifications in Explainable Artificial Intelligence

Alison

Alison online certifications in Machine & Deep Learning in Cybersecurity

Alison

Alison online certifications in Generative Artificial Intelligence for Businesses

Alison

Alison online certifications in Artificial Intelligence for Education & Learning

Alison

Alison online certifications in Artificial Intelligence for Educators

Alison

Alison online certifications in Artificial Intelligence Marketing

Alison

Alison online certifications in Artificial Intelligence Governance & Ethics

Alison

Certification in Chemical Safety and Security Management

Organization for the Prohibition of Chemical Weapons (OPCW)

Certification in Basic Financial Management Principles for Sustainability of Laboratory, Budgeting and Pricing

NIPRD

Certification in Computer Appreciation and Microsoft Office Applications

NIPRD

Certification in nanotechnology and its advances

Society of Pharmaceutical Sciences and Research (SPSR) India

Certification in Recent Trends and Challenges in Regulation and Standardization of Herbal Drugs and Formulations

National Institute of Pharmaceutical Education and Research (NIPER)

Certification in Gas Chromatography-Mass Spectrometry (GC-MS) Analysis and Mass Spectral Interpretation

Royal Society of Chemistry and University of Lagos

Certification in Compendia Technique on Dissolution Testing and Performance Verification n Test (PVT), HPLC Analysis, pH Measurement, and CAPA Program

USP/PQM+, NIPRD

Certified ISO/IEC 17025:2017 Accreditation Technical Assessor

USP/NiNAS

ISO 9001:2015 Quality Management Systems Certified Auditor

Standards Organization of Nigeria (SON)

Certification in Project Management

Nigerian Institute of Medical Research (NIMR), WHO/TDR/RTC

Diploma in Computer (Information Systems Management) Upper Credit

SPED Consultancy Services

Skills

Analytical Chemistry

TLC, FTIR spectroscopy, HPLC, GC-MS, 2D NMR, LC-HR/MS/MS, LC-NMR, LC-NMR-MS, Mass Spectral Interpretation, pH Measurement, Dissolution Testing, Compendia Technique.

Natural Products Chemistry

Medicinal Plant Research, Traditional Medicine, Bioactive Natural Products, Phytochemical Analysis, Extraction, Isolation, Characterization, Standardization, Herbal Drugs, Metabolites Profiling.

Organic Chemistry

Organic Synthesis, Semi-synthetic Modifications, Lead Optimization, Heterocyclic Chemistry.

Quality Management

ISO/IEC 17025, ISO 9001, Quality Assurance, Quality Control, Accreditation, Risk Management, CAPA Program.

Pharmaceutical Sciences

Drug Discovery, Phytomedicine Development, Reference Standards, Pharmaceutical Research, Drug Manufacturing Process Control.

Research & Development

Experimental Optimization, Process Design, Techno-economic Assessment, Uncertainty Analysis, Project Management, Scientific Writing, Peer-Reviewed Publications.

Academia & Supervision

Teaching, Student Supervision (M.Sc, PhD), Curriculum Development, Practical Sessions, Academic Qualifications.

Artificial Intelligence

Task Management & Productivity, Explainable AI, Prompt Engineering, AI Applications, AI Governance & Ethics, AI Marketing, AI for Educators, AI for Education & Learning, Generative AI, Machine Learning, Deep Learning, Cybersecurity.

Nanotechnology

Nanotechnology advances, Silver Nanoparticles.

Project Management

Project Management, Strategic Planning, Coordination, Liaison.

Computer Skills

Computer Appreciation, Microsoft Office Applications, Information Systems Management.

References

Professor Ben A. Chindo

Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna, Nigeria. E-mail: bachindo@kasu.edu.ng Phone: 08032899112

Professor John O. Igoli

Department of Chemistry, College of Science, University of Agriculture, P.M. B. 2373, Makurdi, Nigeria. E-mail: j.o.igoli@uam.edu.ng Phone: 08130991308

Professor Emmanuel Olusola Oke

Chemical Engineering Department, Michael Okpara University of Agriculture, Umudike, Nigeria. E-mail: solaemmanuel1@gmail.com; oke.olusola@mouau.edu.ng Phone: 08034622727